CORE Electron Microscopy Lab and the Microscopy and Image Analysis CORE

Overview of the CORE Electron Microscopy Lab 

Overview of the Microscopy and Image Analysis Core

Contact

Emma Perry, Ph.D.    
Microscopy Lab Manager     
207-581-2566
emma.perry@maine.edu     

Location

11 Murray Hall
University of Maine
Orono, ME 04469

 Google Map

Office Hours

Monday - Friday 8am - 4pm

Links & Resources:

CORE Electron Microscopy Lab

Contact

Zhengxin Ma, Ph.D.    
Microscopy & Image Analysis Core Manager

zhengxin.ma@maine.edu

Location

369 Hitchner Hall
University of Maine
Orono, ME 04469

 Google Map

Office Hours

Monday - Friday 8am - 4pm

Links & Resources:

COBRE MIAC

The Electron Microscopy Laboratory offers the tools and technical expertise for research and training in microscopy with both light and electron microscopes. We maintain and operate electron microscopes (TEM and SEM with EDS), a confocal laser scanning microscope, and the ancillary equipment needed for the preparation of specimens for EM and other microscopy. Our multiple light microscopes encompass optics for bright-field, phase-contrast, differential-interference, and fluorescence imaging.

Technical Services:

• Microscope operation—full operation of all electron and light microscopes.
• Specimen preservation by chemical and microwave-enhanced fixation.
• Specimen embedment in media suitable for TEM or light microscopy.
• Critical-point-drying of specimens for SEM.
• Metal coating of specimens by evaporative or sputter technology.
• Consulting on techniques of microscopy

Established through a COBRE Grant from NIH, the COBRE Microscopy and Image Analysis CORE has two specific aims designed to provide training and access to (1) state-of-the art, high resolution live imaging services and (2) experiment planning, data management and image analysis services.

The Microscopy and Image Analysis Core (MIAC) offers cutting-edge imaging capabilities with its Zeiss LSM980 equipped with AiryScan 2. This advanced microscope supports a wide array of applications, including multi-color experiments, live sample imaging, protein colocalization, tiling of large samples, Z-stack 3D/4D imaging, and weak label detection. Additionally, MIAC provides expert guidance in microscopy and image analysis, as well as comprehensive training and support to advance research across various model organisms. For image analysis, the facility is equipped with Imaris software on a high-performance workstation, ensuring robust and sophisticated data analysis.

Robert Wheeler, Ph.D.

MIAC Facility Director

Robert.wheeler1@maine.edu

Michael Call

CORE Facilities Manager

207-581-3382

Michael.call@maine.edu

Julie Rutherford

CORE Fiscal Officer

207-581-1118

Julie.rutherford@maine.edu

Megan Tardif

CORE Director

207-581-1225

Megan.tardif@maine.edu